Conversion of CO2 into valuable products: Engineering the PirC-PGAM switch in cyanobacteria to direct carbon flux into desired products
Nathalie Sofie Becker, Franziska Hufnagel, Paul Bolay, Kevin Otec, Tim Orthwein, Andreas Kulik, Phillipp Fink, Claudius Lenz, Pia Lindberg, Karl Forchhammer, Stephan Klähn
This paper engineers the PirC-PGAM switch in cyanobacteria to redirect carbon flux toward desired products like sucrose and succinate, demonstrating a tunable control point for metabolic engineering.
Microbial Cell Factories · May 20, 2026Peer-reviewedBioengineering