Epitranscriptomic Reader YTHDF2 Regulates SEK1(MAP2K4)-JNK-cJUN Inflammatory Signaling in Astrocytes during Neurotoxic Stress
Emir Malovic, Alyssa Ealy, Cameron Miller, Ah-Young Jang, Phillip J. Hsu, Souvarish Sarkar, Dharmin Rokad, Cody Goeser, Aleah Kristen Hartman, Allen C. Zhu, Bharathi N. Palanisamy, Gary D. Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, , Anumantha G. Kanthasamy
This study shows YTHDF2 regulates inflammatory signaling in astrocytes during neurotoxic stress by modulating SEK1-JNK-cJUN pathway activation.
iScience · Jul 31, 2024Peer-reviewedNeuroscience