Anumantha G. Kanthasamy

This study shows that PK2 signaling increases GDNF in astrocytes and that modulating PK2 receptors protects neurons in Parkinson's disease models.

This study shows that inhibiting KCa3.1 channels reduces neuroinflammation and dopaminergic neurodegeneration in Parkinson's disease models.

The paper develops a rationally designed PKD1 activator peptide, AK-P4T, which protects against neurodegeneration in pre-clinical Parkinson's disease models.

This study investigates how Kv1.3 and MAPK14 contribute to microglial oxidative stress and neuroinflammation after organic dust exposure, finding that inhibiting Kv1.3 reduces inflammation and oxidative stress markers.

This study identifies Stat3 as a downstream effector of Fyn kinase in dopaminergic neurodegeneration and microglia activation using a zebrafish model.

This study shows YTHDF2 regulates inflammatory signaling in astrocytes during neurotoxic stress by modulating SEK1-JNK-cJUN pathway activation.

This study shows C. difficile infection increases p-cresol and alters dopamine metabolism in mice, linking gut microbiota to neurodevelopmental disorders.

This study shows that mitochondrial dysfunction in Parkinson’s disease models leads to H3K27 hyperacetylation, disrupting active enhancers and epigenetic regulation.