A viral guide RNA delivery system for CRISPR-based transcriptional activation and heritable targeted DNA demethylation in Arabidopsis thaliana
Basudev Ghoshal, Brandon Vong, Colette L. Picard, Feng Suhua, Janet May Tam, Steven E. Jacobsen
This paper develops a tobacco rattle virus-based system for delivering guide RNAs to achieve transcriptional activation and heritable DNA demethylation in Arabidopsis thaliana.
PLOS Genetics · Dec 14, 2020Peer-reviewedPlant Biology