Physiological Cryptic Last Exon Splicing Generates Regulated and Functional Transcript Isoforms Across Vertebrates
Matthew P. Bostock, Karla Lozano Gonzalez, Colin Lentjes, Samina Uddin, Lourdes Osuna Almagro, Fursham Hamid, Corinne Houart
The paper identifies cryptic last exons (CLEs) in vertebrates and shows they generate regulated, functional transcript isoforms with developmental roles.
bioRxiv · Sep 24, 2026 · PreprintNeuroscience