Corinne Houart

The paper identifies cryptic last exons (CLEs) in vertebrates and shows they generate regulated, functional transcript isoforms with developmental roles.

The paper identifies human-specific features of telencephalic patterning in early development using single-cell transcriptomics and spatial imaging, showing delayed ventral SHH signaling and enhanced anterior FGF signaling compared to mice.

The paper shows that a cleaved cytosolic FOXG1 enhances mitochondrial translation and promotes excitatory neurogenesis, offering a new therapeutic target for mitochondrial disorders.

The paper identifies manganese deficiency and neurotoxicity in zebrafish slc39a14 mutants through transcriptome analysis, revealing key molecular pathways involved in manganese homeostasis disruption.

The paper shows that SNRNP70 in axons regulates transcript stability and splice variants, affecting motor connectivity development.

The paper identifies a homozygous SFPQ mutation in a human patient with neurological features and shows its deleterious effects in a zebrafish model.

This study identifies SFPQ's role in repressing cryptic last exons, showing its conservation across species and relevance to neurodegenerative diseases.

This study identifies Slbp as essential for cell cycle exit and neuronal differentiation in zebrafish, leading to retinal and brain defects.