Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell Transplantation
Alexandre Pellan Cheng, Matthew Pellan Cheng, Conor James Loy, Joan Sesing Lenz, Kaiwen Chen, Sami Smalling, Philip Burnham, Kaitlyn Marie Timblin, José Luis Orejas, Emily A. Silverman, Paz Polak, Francisco M. Marty, Jerome Ritz, Iwijn De Vlaminck
This study demonstrates that cell-free DNA analysis can detect multiple post-transplant complications in HCT recipients through methylation, metagenomic, and genomic profiling.
bioRxiv · Apr 25, 2020 · PreprintGenomics