An RNAi screen reveals common host-virus gene signatures: implication for anti-viral drug discovery
David Shum, Bhavneet Bhinder, Jeni P. Mahida, Constantin Radu, Paul A. Calder, Hakim Djaballah
The paper performs an RNAi screen to identify host genes involved in Dengue virus infection, finding 1,730 genes that inhibit infection and 194 that enhance it, and identifies a common gene signature across multiple screens.
bioRxiv · Jul 12, 2022 · PreprintSystems Biology