David Shum

This paper develops recombinant tick-borne encephalitis viruses with reporter genes to guide antiviral testing, finding that Nluc is more stable than eGFP in certain conditions.

The paper performs an RNAi screen to identify host genes involved in Dengue virus infection, finding 1,730 genes that inhibit infection and 194 that enhance it, and identifies a common gene signature across multiple screens.

The paper identifies dsRNA-binding proteins that mediate decitabine's effects by stabilizing ERV RNAs, showing low Stau1 and TINCR expression correlates with poor treatment outcomes in AML patients.