The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis to maintain translational repression of maternal mRNA and oocyte quality
Mohamed T. Elaswad, Mingze Gao, Victoria E. Tice, Cora G. Bright, Grace M. Thomas, Chloe Munderloh, Nicholas J. Trombley, Christya N. Haddad, Ulysses G. Johnson, Ashley N. Cichon, Jennifer A Schisa
The paper identifies novel regulators of RNA-binding protein phase transitions during oogenesis that maintain translational repression of maternal mRNAs and oocyte quality.
Molecular Biology of the Cell · Aug 21, 2024Peer-reviewedDevelopmental Biology