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CRAK-Velo improves RNA velocity estimation by integrating chromatin accessibility data, enabling accurate cell-type deconvolution and insights into gene-chromatin interactions.

This study shows that Toxoplasma gondii infection redirects placental trophoblast lineage specification, promoting infection-permissive cells over infection-resistant ones.

The paper identifies novel regulators of RNA-binding protein phase transitions during oogenesis that maintain translational repression of maternal mRNAs and oocyte quality.

CLADES estimates clone-specific kinetics and fate bias in human cord blood LT-scSeq data using a NeuralODE-Gillespie hybrid approach, improving meta-clone fate prediction accuracy.

UniTVelo improves RNA velocity modeling by incorporating temporal regularization, enhancing trajectory inference across diverse biological systems.

The paper defines the single-cell spatiotemporal gene expression landscape of human embryonic development using stem-cell-derived organoids and identifies key developmental signatures and signaling pathways.