The TWEAK/Fn14 signaling promotes skeletal muscle wasting during cancer cachexia
Meiricris Tomaz da Silva, Anirban Roy, Anh Tuan Vuong, Aniket S. Joshi, Cristeena Josphien, Meghana V. Trivedi, Sajedah M. Hindi, Vihang A. Narkar, Ashok Kumar
This study shows that inhibiting the TWEAK/Fn14 signaling reduces skeletal muscle wasting and tumor growth in cancer cachexia models.
iScience · May 30, 2025Peer-reviewedCell Biology