Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance
Caroline D. Keroack, Brendan Elsworth, Jacob Adam Tennessen, Aditya S. Paul, Renee Hua, Luz Ramirez-Ramirez, Sida Ye, Cristina Moreira, Marvin J. Meyers, Kourosh Zarringhalam, Manoj T. Duraisingh
This paper identifies PhoD as a novel resistance determinant in Babesia species using comparative chemogenomics and validates its role through reverse genetics and functional perturbation.
bioRxiv · Jun 13, 2023 · PreprintMolecular Biology