Metagenomic estimation of absolute bacterial biomass in the mammalian gut through host-derived read normalization.
Gechlang Tang, Alex V. Carr, Crystal Perez, Katherine Ramos Sarmiento, Lisa Levy, Johanna W. Lampe, Christian Diener, Sean M. Gibbons
This paper estimates absolute bacterial biomass in the gut using host-derived read normalization from metagenomic data, showing it tracks antibiotic treatment response in mice and humans.
mSystems · Jul 31, 2025Peer-reviewedMicrobiology