A Constitutively Closed Pannexin1 Channel in Lipid Bilayer Nanodiscs Assembles as a Large-Pore Heptamer
X. Jin, S. A. Leonhardt, Y.-H. Chiu, M. D. Purdy, W. E. McIntire, B. C. Bennett, D. A. Bayliss, M. Yeager
The paper examines a constitutively closed Panx1 channel, showing it assembles as a heptamer in solution and by cryoEM, with structural insights into large-pore channels.
bioRxiv · Dec 31, 2020 · PreprintBiophysics