Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis.
T. P. Burke, P. Engstrom, C. J. Tran, D. R. Glasner, D. A. Espinosa, E. Harris, M. D. Welch
This study shows that interferon receptor-deficient mice develop eschars and lethal disease upon Rickettsia parkeri infection, mimicking human rickettsiosis, and identifies vaccine candidates.
bioRxiv · Sep 23, 2020Microbiology