Adipocyte-secreted IL-6 sensitizes macrophages to IL-4 signaling
D. A. Luan, B. Dadpey, J. Zaid, P. E. Bridge-Comer, J. H. DeLuca, W. Xia, J. Castle, S. M. Reilly
The paper shows that adipocyte-secreted IL-6 enhances macrophage sensitivity to IL-4 signaling through STAT3 activation and Il4ra expression.
bioRxiv · Jul 19, 2022Immunology