Transcription factor TFII-I fine tunes innate properties of B lymphocytes
A. Singh, M. Kaileh, S. De, K. Mazan-Mamczarz, D. Bayarsaihan, R. Sen, A. Roy
This study shows that TFII-I is essential for maintaining innate B cell properties, with its loss causing myeloid-like transcriptomic changes and increased IgG3 switching.
Frontiers in Immunology · Jan 23, 2023Peer-reviewedImmunology