The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing
D. Begolo, I. M. Vincent, F. Giordani, M. J. Witty, T. G. Rowan, Z. Bengaly, K. Gillingwater, Y. Freund, M. P. Barrett, C. E. Clayton
This paper investigates how the benzoxaborole AN7973 kills trypanosomes by inhibiting mRNA processing, identifying it as a viable drug target.
bioRxiv · Apr 7, 2018Microbiology