Androgen Receptor Signaling Regulates the Transcriptome of Prostate Cancer Cells by Modulating Global Alternative Splicing
K. Shah, T. Gagliano, L. Garland, T. O'Hanlon, D. Bortolotti, V. Gentili, R. Rizzo, G. Giamas, M. Dean
This study shows that androgen receptor signaling in prostate cancer cells regulates alternative splicing of genes, contributing to tumor progression and resistance to anti-androgen therapies.
bioRxiv · Nov 2, 2019Cancer Biology