R. Rizzo

Synergizing algorithmic design, photoclick chemistry and multi-material volumetric printing for accelerating complex shape engineering

The paper introduces a method combining algorithmic design, photoclick chemistry, and multi-material printing to rapidly create complex structures for biomedical applications.

Multiscale Hybrid Fabrication: Volumetric Printing Meets Two-Photon Ablation

This paper introduces a hybrid fabrication method combining volumetric printing and two-photon ablation to create multiscale vasculature-like structures for organ-on-a-chip applications.

Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogene

The paper identifies B4GALT5 as a glyco-oncogene by analyzing copy number alterations in glycosylation regulator genes across cancer datasets.

ACE2 expression and localization are regulated by CFTR: implications beyond cystic fibrosis

The paper investigates how CFTR regulates ACE2 expression and localization in airway epithelial cells, showing reduced SARS-CoV-2 infection in CF cells.

The Immunomodulatory Effects of Social Isolation in Mice are Linked to Temperature Control

This study shows that social isolation in mice increases resistance to bacterial sepsis, linked to changes in gene expression and cytokine production, which can be reversed by artificial nesting.

Regulated compartmentalization of enzymes in Golgi by GRASP55 controls cellular glycosphingolipid profile and function

This study identifies GRASP55 as a regulator of enzyme compartmentalization in the Golgi, which controls glycosphingolipid biosynthesis and cellular glycan profiles.

The Glyco-enzyme adaptor GOLPH3 Links Intra-Golgi Transport Dynamics to Glycosylation Patterns and Cell Proliferation

This study shows GOLPH3 regulates glycosylation and cell proliferation by controlling glyco-enzyme recycling and lysosomal degradation.

Androgen Receptor Signaling Regulates the Transcriptome of Prostate Cancer Cells by Modulating Global Alternative Splicing

This study shows that androgen receptor signaling in prostate cancer cells regulates alternative splicing of genes, contributing to tumor progression and resistance to anti-androgen therapies.

The spent culture supernatant of Pseudomonas syringae contains azelaic acid

This study identifies azelaic acid in the spent culture supernatant of Pseudomonas syringae pv. actinidiae as a potential intercellular signal, with structural similarities to quorum sensing molecules.

Sphingolipid metabolic flow controls phosphoinositide turnover at thetrans Golgi network

The paper identifies a homeostatic circuit that regulates sphingolipid levels at the trans Golgi network by linking sphingomyelin production to PtdIns(4)P dephosphorylation, which interrupts cholesterol and sphingolipid transport.