Author

D. Chang-Yen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Radosevich· 2 shared F. Pu· 2 shared J. D. Williams· 2 shared J. W. Sawicki· 2 shared N. L. Elsen· 2 shared N. N. Talaty· 2 shared J. Y. Pan· 1 shared S. A. Ugrin· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

A. J. Radosevich

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2 papers

Recent·Most cited

High Throughput Intact Protein Analysis for Drug Discovery Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

F. Pu, S. A. Ugrin, A. J. Radosevich, D. Chang-Yen, J. W. Sawicki, N. N. Talaty, N. L. Elsen, J. D. Williams

This paper demonstrates the use of IR-MALDESI-MS for high throughput intact protein analysis in drug discovery, achieving faster sample rates than traditional ESI-MS methods.

bioRxiv · Nov 8, 2021Biochemistry

Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

A. J. Radosevich, F. Pu, D. Chang-Yen, J. W. Sawicki, N. N. Talaty, N. L. Elsen, J. D. Williams, J. Y. Pan

This paper develops an ultrahigh-throughput IR-MALDESI mass spectrometry method capable of analyzing 22 samples per second with low carryover and high repeatability.

bioRxiv · Oct 25, 2021 · PreprintPharmacology & Toxicology