Author

D. Cowburn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:ChIP-seq· 1 Organism:Xenopus· 1

Frequent Co-Authors

A. Fiser· 1 shared A. Sali· 1 shared B. M. Lorton· 1 shared B. Raveh· 1 shared C. Warren· 1 shared D. Hunt· 1 shared D. Russel· 1 shared D. Shechter· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Fiser

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2 papers

Recent·Most cited

Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport

B. Raveh, R. Eliasian, S. Rashkovits, D. Russel, R. Hayama, S. Sparks, D. Singh, R. Lim, E. Villa, M. P. Rout, D. Cowburn, A. Sali

The paper constructs an integrative Brownian dynamics model of nucleocytoplasmic transport, revealing how FG repeat proteins and nuclear transport receptors mediate selective transport through NPCs.

bioRxiv · Dec 31, 2023 · PreprintCell Biology

Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA charge mimicry to enhance chaperone efficiency

B. M. Lorton, C. Warren, H. Ilyas, P. Nandigrami, S. Hegde, S. Cahill, S. M. Lehman, J. Shabanowitz, D. Hunt, A. Fiser, D. Cowburn, D. Shechter

The paper shows that glutamylation of acidic IDRs in Npm2 and Nap1 enhances their DNA mimicry function, improving histone chaperone efficiency in nucleosome assembly.

bioRxiv · Sep 18, 2023Biochemistry