Behavioral flexibility in an OCD mouse model: Impaired Pavlovian reversal learning in SAPAP3 mutants
B. J. G. van den Boom, A. H. Mooij, I. Miseviciute, D. Denys, I. Willuhn
This study shows that SAPAP3 knockout mice have impaired Pavlovian reversal learning, indicating cognitive deficits, while their compulsive grooming and anxiety are unrelated traits.
bioRxiv · Oct 6, 2018Animal Behavior & Cognition