Conserved interactions required for in vitro inhibition of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
A. Shitrit, D. Zaidman, O. Kalid, I. Bloch, D. Doron, T. Yarnizky, I. Buch, I. Segev, E. Ben-Zeev, E. Segev, O. Kobiler
The paper identifies conserved hydrogen-bond interactions in SARS-CoV-2 Mpro and screens FDA-approved drugs to find potential inhibitors.
bioRxiv · Sep 10, 2020Microbiology