Lack of apolipoprotein A1 impairs optimal regulatory T cell homeostasis at steady state due to impaired IL-2 signaling
D. E. Gaddis, R. Wu, J. S. Parks, M. G. Sorci-Thomas, C. C. Hedrick
This study shows that ApoA1 deficiency impairs Treg cell homeostasis and function through reduced IL-2 signaling and altered cholesterol content in mice.
bioRxiv · Sep 14, 2019 · PreprintImmunology