Author

D. Frick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

N. R. Silvaggi· 2 shared N. Vuksanovic· 2 shared R. S. Virdi· 2 shared N. C. Hopper· 1 shared N. Dahal· 1 shared R. V. Bavisotto· 1 shared T. R. Melkonian· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

N. R. Silvaggi

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Author profile →

2 papers

Recent·Most cited

Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3

R. S. Virdi, R. V. Bavisotto, N. C. Hopper, N. Vuksanovic, T. R. Melkonian, N. R. Silvaggi, D. Frick

The paper identifies potential ligands for the SARS-CoV-2 Nsp3 Mac1 domain using a high-throughput DSF assay and validates them with molecular docking and structural analysis.

bioRxiv · Jul 6, 2020Biochemistry

Molecular Basis for ADP-ribose Binding to the Macro-X Domain of SARS-CoV-2 Nsp3

D. Frick, R. S. Virdi, N. Vuksanovic, N. Dahal, N. R. Silvaggi

This study investigates the ADP-ribose binding capability of the SARS-CoV-2 nsp3 macrodomain, revealing its structural conservation despite sequence divergence from other coronaviruses.

bioRxiv · Mar 31, 2020Biochemistry