D. H. Goldhill

The paper analyzes SARS-CoV-2 variant virion morphology and spike protein structures using cryo-EM, finding no adaptive changes in virion shape but multiple amino acid changes affecting spike conformational dynamics.

The paper identifies spike mutations that adapt SARS-CoV-2 to mustelid hosts and assesses their impact on human infectivity and antigenicity.

This study shows that SARS-CoV-2 variant B.1.1.7 does not replicate better in airway cells or escape antibodies, suggesting its increased transmissibility is due to other factors.

This study shows the furin cleavage site in SARS-CoV-2 spike protein enhances replication in airway cells, contributing to transmission efficiency.

This study shows swine ANP32A supports avian influenza polymerase activity, and human-adapted viruses evolved to use human ANP32 proteins more efficiently.

This study examines how egg adaptation of the H3N2 influenza vaccine strain affects antibody responses in children, finding higher seroconversion rates to the adapted strain but differential mucosal IgA responses based on prior serostatus.