Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal mechanism for maximal T cell migration speeds
R. Alonso Matilla, D. I. Pedro, A. Pepe, J. Serrano-Velez, M. Dunne, D. T. Nguyen, W. G. Sawyer, P. P. Provenzano, D. J. Odde
This study identifies that T cells achieve maximal migration speeds by combining bleb formation with adhesion-based forces, challenging the feasibility of adhesion-free migration.
bioRxiv · Oct 29, 2023Biophysics