Development of High-Throughput Screening Assays for Inhibitors of ETS Transcription Factors
S. Currie, S. L. Warner, H. Vankayalapati, X.-H. Liu, S. Sharma, D. J. Bearss, B. J. Graves
The paper develops two in vitro assays to screen inhibitors of ETS transcription factors and finds that lower affinity DNA-binding sequences enhance compound inhibition.
bioRxiv · Aug 28, 2017Biochemistry