The Role of the Ovarian Cancer G -Coupled Receptor (OGR1) in Idiopathic Pulmonary Fibrosis
D. J. Nagel, R. Clough, T. J. Bell, W.-Y. Ku, P. Sime, M. Kottmann
This study identifies OGR1 as a negative regulator of fibrotic signaling in IPF, showing reduced OGR1 expression in IPF lung tissue and its role in inhibiting myofibroblast differentiation and TGF-β activation.
bioRxiv · Nov 20, 2019 · PreprintCell Biology