Immunosuppressive role of PGE2 during human tuberculosis
J. M. Pellegrini, N. L. Tateosian, M. P. Morelli, A. Rolandelli, N. O. Amiano, D. J. Palmero, A. Levi, L. Ciallella, M. I. Colombo, V. E. Garcia
This study shows PGE2 suppresses immune responses in human tuberculosis by inhibiting lymphoproliferation, cytokine production, and immunological receptor expression, while promoting autophagy in monocytes.
bioRxiv · Aug 4, 2020 · PreprintImmunology