Rab12 regulates LRRK2 activity by promoting its localization to lysosomes
V. V. Bondar, X. Wang, O. B. Davis, M. T. Maloney, M. Agam, M. Y. Chin, A. C.-N. Ho, D. Joy, J. W. Lewcock, G. Di Paolo, R. G. Thorne, Z. K. Sweeney, A. G. Henry
This study identifies Rab12 as a regulator of LRRK2 activity by promoting its localization to lysosomes, leading to increased phosphorylation of Rab10.
bioRxiv · Feb 21, 2023 · PreprintCell Biology