Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation
V. Navratna, D. K. Tosh, K. A. Jacobson, E. Gouaux
This study identifies a thermostable variant of the human dopamine transporter (hDAT) and describes a method to purify it in an inhibitor and allosteric ligand bound conformation.
bioRxiv · May 31, 2018Biochemistry