Author

V. Navratna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:protein structure prediction· 3 Assay:protein structure· 2 Assay:structural biology· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Kumar· 2 shared E. Gouaux· 2 shared J. K. Rana· 2 shared S. Mosalaganti· 2 shared D. Antermite· 1 shared D. K. Tosh· 1 shared D. Yang· 1 shared J. A. Bull· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. Kumar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain

V. Navratna, A. Kumar, J. K. Rana, S. Mosalaganti

The paper reports the structure of hSIDT1, revealing its lipid binding domain's conformational flexibility and structural features.

bioRxiv · Dec 21, 2023Biophysics

Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)

V. Navratna, A. Kumar, J. K. Rana, S. Mosalaganti

This study determines the high-resolution structure of HGSNAT-acetyl-CoA complex using cryo-EM and maps MPS IIIC mutations to elucidate dysfunction mechanisms.

bioRxiv · Oct 23, 2023Biophysics

Chemical and structural investigation of the paroxetine-human serotonin transporter complex

J. A. Coleman, V. Navratna, D. Antermite, D. Yang, J. A. Bull, E. Gouaux

The paper investigates the binding of paroxetine and its analogs to the serotonin transporter using structural and biochemical methods, revealing how they stabilize the outward-open conformation and inhibit serotonin transport.

bioRxiv · Feb 26, 2020Biochemistry

Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation

V. Navratna, D. K. Tosh, K. A. Jacobson, E. Gouaux

This study identifies a thermostable variant of the human dopamine transporter (hDAT) and describes a method to purify it in an inhibitor and allosteric ligand bound conformation.

bioRxiv · May 31, 2018Biochemistry