The alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic
A. T. Burton, D. Kalalova, E. V. Snider, L. Krasny, D. B. Kearns
This study shows that the alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic when overexpressed, leading to cell death by outcompeting the vegetative sigma factor SigA for RNA polymerase core binding.
bioRxiv · Mar 22, 2023 · PreprintMicrobiology