J. Stuelke

Control of asparagine homeostasis in Bacillus subtilis: Identification of promiscuous amino acid importers and exporters

This paper identifies asparagine transporters in Bacillus subtilis using genetic screens and toxic analogs, revealing promiscuous importers and exporters for L-asparagine.

Metabolic rewiring compensates for the loss of glutamate and aspartate biosynthesis in Bacillus subtilis

This study identifies a non-canonical fumarate-based ammonium assimilation pathway in B. subtilis that compensates for glutamate and aspartate biosynthesis defects.

ListiWiki: a database for the foodborne pathogen Listeria monocytogenes

ListiWiki is a database that provides comprehensive genomic and functional information on Listeria monocytogenes, including gene annotations, protein interactions, and structural data.

Control of iron homeostasis by a regulatory protein-protein interaction in Bacillus subtilis: The FurA (YlaN) acts as an antirepressor to the ferric uptake regulator Fur

The paper identifies FurA as an antirepressor of Fur in Bacillus subtilis, showing it prevents Fur from binding DNA under iron limitation, thus regulating iron uptake genes.

The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis

The paper identifies RnpM (YlxR) as a novel modulator of RNase P activity in B. subtilis, reducing its ability to process pre-tRNAs.

c-di-AMP determines the hierarchical organization of bacterial RCK proteins

The paper investigates the role of c-di-AMP in regulating bacterial RCK proteins, showing that KtrC is dominant in K+ transport inhibition while KtrA is insensitive, and that c-di-AMP determines the hierarchical organization of these proteins.

Ornithine is the central intermediate in the arginine degradative pathway and its regulation in Bacillus subtilis

This paper identifies ornithine as the central intermediate in the arginine and citrulline degradation pathway in Bacillus subtilis and shows it activates the transcription regulator RocR.

PAE Viewer: A webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks

The paper introduces PAE Viewer, a webserver for visualizing predicted aligned error in protein complex structures and integrating cross-linking data to assess prediction reliability.

A rendezvous of two second messengers: The c-di-AMP receptor protein DarB controls (p)ppGpp synthesis in Bacillus subtilis

This study identifies DarB as a c-di-AMP receptor that interacts with Rel to regulate (p)ppGpp synthesis in Bacillus subtilis under low potassium conditions.

The YtrBCDEF ABC transporter is involved in the control of social activities in Bacillus subtilis

This study identifies the YtrBCDEF ABC transporter as a regulator of genetic competence and biofilm formation in Bacillus subtilis by affecting cell wall properties and ComK activity.

Quasi-essentiality of RNase Y in Bacillus subtilis is caused by its critical role in the control of mRNA homeostasis

This study shows that RNase Y is quasi-essential in Bacillus subtilis due to its role in mRNA homeostasis, as suppressor mutations in RNA polymerase subunits alleviate its deletion effects.

Resistance to serine in Bacillus subtilis: Identification of the serine transporter YbeC and of a metabolic network that links serine and threonine metabolism

This study identifies YbeC as the major serine transporter in Bacillus subtilis and reveals a metabolic link between serine and threonine that causes serine toxicity.