Author

D. Le Duc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Garten· 1 shared A. Koerner· 1 shared A. Krishnan· 1 shared A. S. Kirstein· 1 shared A. Weyrich· 1 shared D. A. Duchene· 1 shared F. Dalerum· 1 shared J. Breitfeld· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Garten

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines

M. Boeschen, S. Horn, D. Le Duc, M. Stiller, M. von Laffert, T. Schönberg

The paper introduces a webtool for analyzing drug sensitivity and resistance in cancer cell lines using genetic data from the GDSC and CCLE databases.

bioRxiv · Aug 22, 2022Cancer Biology

PTEN regulates adipocyte progenitor growth, differentiation and replicative aging

A. S. Kirstein, S. Kehr, M. Nebe, M. Hanschkow, J. Lorenz, M. Penke, J. Breitfeld, D. Le Duc, K. Landgraf, A. Koerner, P. Kovacs, P. F. Stadler, W. Kiess, A. Garten

This study shows PTEN regulates adipocyte progenitor growth, differentiation, and aging by modulating FOXO1 and SREBP1 pathways, contributing to lipoma development in PHTS.

bioRxiv · Jan 5, 2021 · PreprintCell Biology

Ecological specialisation and evolutionary reticulation in extant Hyaenidae

M. V. Westbury, D. Le Duc, D. A. Duchene, A. Krishnan, S. Prost, S. Rutschmann, J. H. Grau, A. Weyrich, K. Noren, L. Werdelin, F. Dalerum, T. Schoeneberg, M. Hofreiter

This study generates an aardwolf genome and analyzes it with other hyena genomes to explore evolutionary relationships, dietary adaptations, and genetic diversity patterns in Hyaenidae.

bioRxiv · Oct 14, 2020Evolutionary Biology