Stochastic Analysis Demonstrates the Dual Role of Hfq in Chaperoning E. coli Sugar Shock Response
D. M. Bianchi, T. A. Brier, A. Poddar, M. S. Azam, C. K. Vanderpool, T. Ha, Z. Luthey-Schulten
The paper uses single-cell microscopy and stochastic modeling to show Hfq stabilizes SgrS and aids its interaction with target mRNA during glucose-phosphate stress in E. coli.
bioRxiv · Jun 30, 2020Biophysics