Author

Z. Luthey-Schulten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Burt· 1 shared A. D. Hanson· 1 shared A. Desfosses· 1 shared A. F. Yakunin· 1 shared A. Hamm· 1 shared A. J. Steelman· 1 shared A. M. Abdel-Hamid· 1 shared A. M. Thamm· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Burt

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metabolite Damage and Damage-Control in a Minimal Genome

D. Haas, A. M. Thamm, J. Sun, L. Huang, L. Sun, G. A. W. Beaudoin, K. S. Wise, C. Lerma-Ortiz, S. D. Bruner, M. Breuer, Z. Luthey-Schulten, J. Lin, M. A. Wilson, G. Brown, A. F. Yakunin, , V. de Crecy-Lagard

The paper identifies and validates genes involved in metabolite damage repair and preemption in the minimized Mycoplasma JCVI-Syn3A genome and extends its metabolic map.

bioRxiv · Dec 1, 2021Microbiology

Stochastic Analysis Demonstrates the Dual Role of Hfq in Chaperoning E. coli Sugar Shock Response

D. M. Bianchi, T. A. Brier, A. Poddar, M. S. Azam, C. K. Vanderpool, T. Ha, Z. Luthey-Schulten

The paper uses single-cell microscopy and stochastic modeling to show Hfq stabilizes SgrS and aids its interaction with target mRNA during glucose-phosphate stress in E. coli.

bioRxiv · Jun 30, 2020Biophysics

Gut bacteria convert cortisol into a distinct hostsignalling molecule

M. Freiberg, T. Wang, R. S. d. L. Rosa, A. Osswald, M. C. R. Melo, D. G. Stouffer, P. S. Buobu, C. Welsh, L. Yang, A. M. Abdel-Hamid, H. L. Doden, S. Devendran, R. M. Pollet, S. Goldberg, L. Ray, , J. M. Ridlon

The paper shows gut bacteria convert cortisol into 20-dihydrocortisol, a distinct host signalling molecule that reprograms colonic transcription and activates inflammatory pathways via NR4A3.

bioRxiv · Jun 12, 2020 · PreprintMicrobiology

Complete structure of the core signalling unit of the E. coli chemosensory array in an optimised minicell strain

A. Burt, C. K. Cassidy, P. Ames, M. Bacia-Verloop, M. Baulard, K. Huard, Z. Luthey-Schulten, A. Desfosses, P. J. Stansfeld, W. Margolin, J. S. Parkinson, I. Gutsche

The paper presents a 3D map of the E. coli chemosensory core signalling unit using cryo-ET and subtomogram averaging, combined with molecular dynamics simulations to create an atomistic model.

bioRxiv · Aug 5, 2019Cell Biology

An In-Silico Mammalian Whole-Cell Model Reveals the Influence of Spatial Organization on RNA Splicing Efficiency

Z. Ghaemi, J. Peterson, M. Gruebele, Z. Luthey-Schulten

The paper develops a spatially-resolved whole HeLa cell model to study how spatial organization affects RNA splicing efficiency and particle assembly.

bioRxiv · Oct 8, 2018Biophysics