Resistance to abemaciclib is associated with increased metastatic potential and lysosomal protein deregulation in breast cancer cells
E. R. Sheidemann, D. M. Demas, C. Hou, J. Ma, W. He, K. N. Weilbaecher, A. N. Shajahan-Haq
This study shows that abemaciclib resistance in breast cancer cells is linked to increased metastatic potential and lysosomal protein deregulation, with potential therapeutic implications for combining lysosomal destabilizers.
bioRxiv · Apr 17, 2023Cancer Biology