BDNF Overexpression in the Prelimbic Cortex Does Not Reduce Anxiety- and Depression-like Behavior in Serotonin Knockout Rats
D. M. Diniz, K. Bosch, F. Calabrese, P. Brivio, M. A. Riva, J. Grandjean, J. R. Homberg
This study investigates whether BDNF overexpression in SERT-/- rats rescues anxiety- and depression-like behaviors, finding no rescue and HPA-axis dysfunction in wild-type rats.
bioRxiv · Jul 1, 2020 · PreprintAnimal Behavior & Cognition