Methotrimeprazine exerts antiviral and neuroprotective effects in Japanese encephalitis virus infection through activation of adaptive ER stress and autophagy
S. K. Prajapat, L. Mishra, S. Khera, S. D. Owusu, K. Ahuja, P. Sharma, R. Singh, D. Mahajan, A. Banerjee, R. K. Motiani, S. Vrati, M. Kalia
This study identifies Methotrimeprazine as a drug that reduces JEV infection through autophagy and ER stress, with neuroprotective and antiviral effects in a mouse model.
bioRxiv · Apr 5, 2023 · PreprintMicrobiology