D. Mattanovich

Efficient production of itaconic acid from the single carbon substrate methanol with engineered Komagataella phaffii

This study engineers Komagataella phaffii to produce itaconic acid from methanol, achieving titers of 55 g/L and a yield of 0.24 g/g.

A native phosphoglycolate salvage pathway of the synthetic autotrophic yeast Komagataella phaffii

The paper identifies a native phosphoglycolate salvage pathway in Komagataella phaffii that recycles 2-phosphoglycolate, similar to plant pathways, and suggests it can enhance autotrophic growth.

The oxygen tolerant reductive glycine pathway in eukaryotes: a native methanol, formate and CO2 assimilation pathway in the yeast Komagataella phaffii

The paper identifies a native pathway in Komagataella phaffii that can assimilate methanol, formate, and CO2, offering potential for industrial bioprocesses.