Hijacking the transcriptional activation potential of the BAF complex via Induced Proximity
L. Chia, D. Mayhew, B. Sherbanee, D. L. Lahr, A. M. Taherbhoy
This study uses induced proximity to redirect BAF complexes to activate therapeutic genes, altering chromatin landscapes and identifying proliferation-suppressing genes.
bioRxiv · Dec 18, 2023 · PreprintCell Biology