Author

L. Chia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Echterhof· 1 shared A. Frymoyer· 1 shared A. K. Aragaki· 1 shared A. M. Taherbhoy· 1 shared B. A. Johnson· 1 shared B. Sherbanee· 1 shared C.-C. Shen· 1 shared D. Dordai· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. Echterhof

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo

A. Echterhof, T. Dharmaraj, R. McBride, J. D. Berry, M. Hopkins, H. Selvakumar, K.-Y. Lin, L. Chia, C.-C. Shen, W. Lioa, P. Lee, T. Yeh, G. Suh, F. G. Blankenberg, A. Frymoyer, P. Bollyky

This study examines how neutrophils affect bacteriophage clearance and pharmacokinetics in mice, finding minimal impact from neutrophils but significant inactivation of phages over time.

JCI Insight · Oct 22, 2024Peer-reviewedPharmacology & Toxicology

Hijacking the transcriptional activation potential of the BAF complex via Induced Proximity

L. Chia, D. Mayhew, B. Sherbanee, D. L. Lahr, A. M. Taherbhoy

This study uses induced proximity to redirect BAF complexes to activate therapeutic genes, altering chromatin landscapes and identifying proliferation-suppressing genes.

bioRxiv · Dec 18, 2023 · PreprintCell Biology

The indoleamine 2,3 dioxygenase pathway drives intratumoral B cell maintenance.

B. A. Johnson, A. K. Aragaki, D. M. Williams, O. Rogers, J. Mountain, L. Luo, W. Zhang, L. Xian, M. Feng, L. Chia, D. Dordai, N. M. Hahn, S. Desiderio, T. S. Johnson, D. J. McConkey, L. M. S. Resar

This study shows that inhibiting the IDO1 pathway reduces tumor-infiltrating B cells in melanoma models, suggesting potential therapeutic strategies for solid tumors.

bioRxiv · Aug 25, 2021 · PreprintImmunology