Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for anti-malarial intervention deployment.
H. Njoroge, A. van't Hof, A. Oruni, D. Pipini, S. C. Nagi, A. Lynd, E. R. Lucas, S. Tomlinson, X. Grau-Bove, D. McDermott, F. t. Wat'senga, E. Z. Manzambi, F. R. Agossa, A. Mokuba, S. R. Irish, , M. J. Donnelly
The paper identifies a triple mutant in Anopheles gambiae associated with pyrethroid resistance and proposes it as a diagnostic for guiding anti-malarial intervention strategies.
bioRxiv · Feb 11, 2021 · PreprintEvolutionary Biology