Author

S. Tomlinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 2 Ecology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Research Focus:ecology & biodiversity· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

D. Weetman· 3 shared M. J. Donnelly· 3 shared A. Oruni· 2 shared X. Grau-Bove· 2 shared A. Anderson· 1 shared A. E. Van't Hof· 1 shared A. Lynd· 1 shared A. M. Jacobi· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersEvolutionary Biology

D. Weetman

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Author profile →

7 papers

Recent·Most cited

Reconstructing colonization dynamics to establish how human activities transformed island biodiversity

S. Tomlinson, M. Lomolino, S. Haythorne, A. Anderson, J. Austin, S. C. Brown, G. Perry, J. Wilmshurst, J. Wood, D. A. Fordham

The paper develops a process-explicit method to reconstruct human colonization dynamics on islands, showing it can reveal how human activities transformed biodiversity in New Zealand.

bioRxiv · Feb 9, 2023Ecology

Fifty years of reduction in sulphur deposition drives recovery in soil pH and plant communities

F. M. Seaton, D. A. Robinson, D. Monteith, I. Lebron, P. Buerkner, S. Tomlinson, B. A. Emmett, S. M. Smart

The paper shows that reduced sulphur deposition has led to soil pH recovery and plant community changes in semi-natural habitats, but not in intensively managed grasslands.

bioRxiv · Jul 4, 2022Ecology

B1 SINE-binding ZFP266 impedes reprogramming through suppression of chromatin opening mediated by pioneering factors

D. F. Kaemena, M. Yoshihara, J. Ashmore, M. Beniazza, S. Zhao, M. Bertenstam, V. Olariu, S. Katayama, K. Okita, S. Tomlinson, K. Yusa, K. Kaji

This study identifies ZFP266 as a reprogramming roadblock gene that suppresses chromatin opening by binding SINEs near pioneer factor binding sites, and shows that replacing its KRAB domain with a co-activator domain enhances reprogramming.

bioRxiv · Jan 4, 2022 · PreprintCell Biology

Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for anti-malarial intervention deployment.

H. Njoroge, A. van't Hof, A. Oruni, D. Pipini, S. C. Nagi, A. Lynd, E. R. Lucas, S. Tomlinson, X. Grau-Bove, D. McDermott, F. t. Wat'senga, E. Z. Manzambi, F. R. Agossa, A. Mokuba, S. R. Irish, , M. J. Donnelly

The paper identifies a triple mutant in Anopheles gambiae associated with pyrethroid resistance and proposes it as a diagnostic for guiding anti-malarial intervention strategies.

bioRxiv · Feb 11, 2021 · PreprintEvolutionary Biology

Evolution of the insecticide target Rdl in African Anopheles is driven by interspecific andinterkaryotypic introgression

X. Grau-Bove, S. Tomlinson, A. O. O'Reilly, N. J. Harding, A. Miles, D. Kwiatkowski, M. J. Donnelly, D. Weetman, The Anopheles gambiae 1000 Genomes Consortium

The paper examines the evolution of insecticide resistance in Anopheles mosquitoes, showing how Rdl mutations spread through selective sweeps and introgression across species and karyotypes.

bioRxiv · Dec 17, 2019Evolutionary Biology

Open source 3D printable replacement parts for the WHO insecticide susceptibility bioassay system

S. Tomlinson, H. Carrington Yates, A. Oruni, H. N. Ng'ang'a, D. Weetman, M. J. Donnelly, A. E. Van't Hof

The paper provides 3D printable replacement parts for the WHO insecticide susceptibility bioassay system to address supply chain issues and enable rapid production.

bioRxiv · Sep 13, 2019Evolutionary Biology

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein

P. S. Dewari, B. Southgate, K. Mccarten, G. Monogarov, E. O'Duibhir, N. Quinn, A. Tyrer, C. Plumb, C. Blin, R. Finch, R. B. Bressan, G. Morrison, A. M. Jacobi, M. A. Behlke, A. von Kriegsheim, , S. M. Pollard

The paper introduces an efficient, selection-free, and scalable CRISPR/Cas9-based pipeline for epitope tagging in mammalian stem cells, achieving knock-in efficiencies of 5-30%.

bioRxiv · Jan 29, 2018Cell Biology