Identification of Tumor-Reactive B Cells and Systemic IgG in Breast Cancer Based on Clonal Frequency in the Sentinel Lymph Node
J. R. McDaniel, S. C. Pero, W. N. Voss, G. S. Shukla, Y. Sun, S. Schaetzle, C.-H. Lee, A. P. Horton, S. Harlow, J. Gollihar, J. W. Ellefson, C. C. Krag, Y. Tanno, N. Sidiropoulos, G. Georgiou, , D. N. Krag
The paper identifies tumor-reactive B cells in sentinel lymph nodes and links them to systemic IgG antibodies in breast cancer patients using high-throughput sequencing and immunoproteomics.
bioRxiv · Nov 1, 2017Immunology