Author

G. C. Ippolito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 7

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Approach:experimental assay· 6 Assay:proteomics· 6 Research Focus:cell type annotation· 5 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. Georgiou· 4 shared W. N. Voss· 3 shared A. Herbert· 2 shared A. P. Horton· 2 shared D. M. Towers· 2 shared J. D. Gollihar· 2 shared J. Dye· 2 shared J. J. Lavinder· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

G. Georgiou

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

W. N. Voss, M. A. Mallory, P. O. Byrne, J. M. Marchioni, S. A. Knudson, J. M. Powers, S. R. Leist, B. Dadonaite, D. R. Townsend, J. Kain, Y. Huang, E. Satterwhite, I. N. Castillo, M. Mattocks, C. Paresi, , G. C. Ippolito

This study compares IgG antibody responses from SARS-CoV-2 infection, vaccination, and hybrid immunity, finding that hybrid immunity retains the imprint of the initial exposure and enhances antibody breadth and affinity.

Cell Reports Medicine · Aug 1, 2024Peer-reviewedImmunology

Infant antibody repertoires during the first two years of influenza vaccination

M. Kuraoka, N. C. Curtis, A. Watanabe, H. Tanno, S. Shin, K. Ye, E. Macdonald, O. Lavidor, S. Kong, T. Von Holle, I. W. Windsor, G. C. Ippolito, G. Georgiou, E. B. Walter, G. H. Kelsoe, , J. Lee

This paper studies how influenza vaccination in infants shapes their antibody responses, finding that vaccination can lead to immune imprinting similar to infection, with shifts in B-cell specificity and adult-like antibody repertoires after the second year.

bioRxiv · Sep 13, 2022Immunology

THE MAJOR ROLE OF JUNCTIONAL DIVERSITY IN THE HORSE ANTIBODY REPERTOIRE

C. Navas, T. Manso, F. Martins, L. Minto, R. Moreira, J. Minozzo, B. Antunes, J. McDaniel, A. M. Vale, G. C. Ippolito, L. F. Felicori

This study characterizes the horse antibody heavy chain repertoire, revealing high junctional diversity and limited VJ gene usage, highlighting its role in generating antibody variability.

bioRxiv · Jun 20, 2022Immunology

A comparative analysis of memory B cell and antibody responses against Plasmodium falciparum merozoite surface protein 1 in children and adults from Uganda

S. J. Gonzales, K. N. Clarke, G. Batugedara, A. E. Braddom, R. Garza, R. A. Reyes, I. Ssewanyana, K. C. Garrison, G. C. Ippolito, B. M. Greenhouse, S. Bol, E. M. Bunnik

The paper compares memory B cell and antibody responses against Plasmodium falciparum MSP1 in Ugandan children and adults, showing shifts from IgM to IgG and diversification with exposure.

bioRxiv · Nov 4, 2021Immunology

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

W. N. Voss, Y. J. Hou, N. V. Johnson, J. E. Kim, G. Delidakis, A. P. Horton, F. Bartzoka, C. J. Paresi, Y. Tanno, S. A. Abbasi, W. Pickens, K. George, D. R. Boutz, D. M. Towers, J. R. McDaniel, , G. C. Ippolito

The paper identifies prevalent, protective, and convergent IgG antibodies targeting non-RBD epitopes of SARS-CoV-2 spike protein in convalescent plasma.

bioRxiv · Dec 20, 2020Immunology

Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

E. Salazar, S. V. Kuchipudi, P. A. Christensen, T. N. Eagar, X. Yi, P. Zhao, Z. Jin, S. W. Long, R. J. Olsen, J. Chen, B. Castillo, C. Leveque, D. M. Towers, J. Lavinder, J. D. Gollihar, , J. M. Musser

This study finds a strong correlation between anti-RBD and anti-ECD IgG titers and in vitro virus neutralization titers in convalescent plasma, suggesting these titers can serve as surrogates for neutralizing activity.

bioRxiv · Jun 8, 2020Immunology

Identification of Tumor-Reactive B Cells and Systemic IgG in Breast Cancer Based on Clonal Frequency in the Sentinel Lymph Node

J. R. McDaniel, S. C. Pero, W. N. Voss, G. S. Shukla, Y. Sun, S. Schaetzle, C.-H. Lee, A. P. Horton, S. Harlow, J. Gollihar, J. W. Ellefson, C. C. Krag, Y. Tanno, N. Sidiropoulos, G. Georgiou, , D. N. Krag

The paper identifies tumor-reactive B cells in sentinel lymph nodes and links them to systemic IgG antibodies in breast cancer patients using high-throughput sequencing and immunoproteomics.

bioRxiv · Nov 1, 2017Immunology